Built on biology.
Not trends.
Every formula in the MYOCODE system was built around four converging areas of longevity science — and nine months of refusing to compromise on the quality of what went inside. Here is the research that earned every ingredient its place.
Four things happen to the body after 40.
MYOCODE addresses all of them.
Each pillar represents a distinct biological shift that begins in midlife and compounds over decades. The MYOCODE system was formulated to address all four simultaneously — because they don’t happen in isolation.†
Muscle becomes harder to build —
and easier to lose.
Beginning in our late 30s and 40s, muscle becomes progressively less sensitive to protein and exercise — a phenomenon called anabolic resistance. The same workout that built muscle at 30 produces a weaker response at 50. The same gram of protein triggers a weaker synthesis signal.
Without targeted support, adults can lose 3–8% of muscle mass per decade after 30. This isn’t cosmetic. Muscle is the body’s metabolic engine — regulating energy, supporting healthy weight, protecting joints, and determining functional independence in older age.†
MYOCODE addresses this with clinical-dose creatine (5g), HMB (3g) to help support muscle preservation, and a leucine-enriched protein designed to clear the higher synthesis threshold aging muscle requires.†
See the full research →Cellular energy production
declines with age.
NAD+ is essential for mitochondrial energy production, DNA repair signaling, and cellular stress resistance. Research consistently shows NAD+ levels decline with age — in some tissues by 30–50% by midlife. [1]
This decline shows up as lower energy, slower recovery, reduced metabolic flexibility — even in people who train and eat well. The mitochondria that power every cell simply become less efficient over time.†
MYO Daily includes 350mg of Nicotinamide Riboside (NR) — a direct NAD+ precursor shown in human clinical trials to safely support NAD+ levels — alongside creatine, which supports ATP regeneration in the cells that need it most.†
See the full research →The gut changes — and what
you absorb changes with it.
Digestive enzyme production declines with age. The gut microbiome shifts. Even a disciplined nutrition protocol can deliver less to muscle tissue than it should — not because of what you’re eating, but because of how efficiently it’s being absorbed.†
Most plant proteins compound this. Concentrates carry anti-nutrients that reduce bioavailability. High-fermentation fibers cause the bloating that drives people away from plant protein entirely.†
MYOCODE Protein was designed around this: isolates only, a three-fiber prebiotic matrix chosen for tolerance, and a broad-spectrum enzyme blend to maximize what actually reaches muscle.†
See the full research →Even clean eating leaves gaps
that matter in midlife.
Soil depletion, food processing, and the realities of modern life mean that even disciplined nutrition cannot reliably hit the micronutrient levels that aging muscle and cellular health require. Magnesium deficiency is widespread. Vitamin D insufficiency is common.†
The leucine threshold for muscle protein synthesis after 40 is difficult to reach consistently from food alone — particularly on a plant-based diet. The body needs targeted support, not just more food.†
MYOCODE fills these gaps with intention: bioavailable magnesium, vitamins D3 and K2, natural vitamin C, electrolytes, and the leucine dosing aging muscle actually needs.†
See the full research →Nine months.
When everyone said
six weeks was enough.
Most supplement formulas take four to six weeks to develop. A contract manufacturer presents a standard base, minor adjustments are made, and the product ships. MYOCODE took nine months. Not because of delays — because of standards.
Christine developed the formulas herself, drawing on years of personal formulation and biomarker tracking. She then partnered with a clinical biochemist with decades of experience in nutritional supplement development — someone whose career has been spent at the intersection of formulation science and real-world efficacy. Their role: validate the formulas, challenge every ingredient decision, and source the cleanest possible version of each compound.
“I was told, more than once, to reduce the quality. That people care more about price than ingredients. I refused every time.”
What they discovered during sourcing was striking: the majority of supplement ingredients on the market use corn as a carrier — a detail most brands never disclose and most consumers never know to ask about. Finding verified corn-free, clean-carrier versions of every ingredient required going far beyond standard supplier channels.
The result is a formula that took longer and cost more to build — and that Christine uses every single day, gives to her family, and stands behind completely.
Months of formulation and sourcing
What is standard in six weeks took nine — because every ingredient had to meet a higher bar than the industry standard. No shortcuts were taken.
Validated by a clinical biochemist
A formulation scientist with decades of nutritional supplement experience reviewed and validated every ingredient decision and sourcing choice before finalization.
Corn-free carriers — rare in this industry
Most supplement ingredients use corn as a carrier. Finding verified corn-free versions of each active required supplier sourcing well beyond standard channels.
Refused to reduce quality for price
Multiple advisors suggested reducing ingredient quality to improve margins. Every suggestion was declined. Clinical dosing and clean sourcing were non-negotiable from the start.
NSF Certified GMP facility
Manufactured to the highest third-party quality certification standards in the supplement industry. Tested, transparent, and traceable at every step.
The full science —
every claim, every study.
What follows is the complete scientific rationale behind each pillar of the MYOCODE system, including the peer-reviewed research that informed every ingredient and dose. All studies are cited in full in the references section below.
Anabolic resistance — what the research shows
Anabolic resistance refers to the blunted muscle protein synthesis response to protein and exercise that occurs with aging. Multiple studies demonstrate that older adults require a higher leucine stimulus per serving — estimated at 2.5–3g — to achieve comparable rates of muscle protein synthesis to younger adults. [6] This is the primary reason protein quality and leucine content matter more, not less, as we age.
Creatine monohydrate — decades of evidence
Creatine monohydrate at 3–5g/day is supported by decades of peer-reviewed research for improvements in muscle strength, power output, and lean mass support. In older adults, creatine alongside resistance training has been shown to support improvements in muscle function and body composition. [5] The 5g dose in MYOCODE MYO Daily reflects the dose most consistently used across clinical literature.†
HMB — anti-catabolic protection
Beta-hydroxy beta-methylbutyrate (HMB) helps support muscle preservation by reducing muscle protein breakdown and supporting muscle cell membrane integrity. Clinical studies show 3g/day helps support lean mass in aging adults, including during periods of reduced training. [2,3] HMB’s primary value is preservation — making it especially relevant on rest days and through the periods of reduced activity that become more frequent in midlife.†
Supports ATP regeneration, strength, and power output. 5g is the dose used consistently in clinical research showing meaningful muscle outcomes in older adults.†
Kreider RB et al. JISSN 2017 [5]Helps support muscle preservation between workouts. 3g is the clinically studied dose shown to support lean mass in aging and dieting adults.†
Wilson JM et al. BJN 2013 [3]; Hoffman JR et al. JISSN 2009 [2]Complete amino acid profile. Isolates chosen for higher protein density and reduced anti-nutrient fraction vs. concentrates — critical for aging digestion.†
Churchward-Venne TA et al. J Nutr 2012 [6]Primary trigger for muscle protein synthesis via mTOR. Added to help meet the post-40 leucine threshold that plant protein alone may not reliably reach.†
Churchward-Venne TA et al. J Nutr 2012 [6]NAD+ decline — what the research shows
NAD+ is central to mitochondrial energy production and cellular repair signaling. Human studies have documented significant age-associated NAD+ declines across multiple tissue types — with some research showing reductions of 30–50% by midlife. [1] This decline correlates with reduced cellular energy efficiency, slower recovery, and diminished metabolic resilience even in active adults.
Nicotinamide Riboside — a direct NAD+ precursor
NR is a form of vitamin B3 that serves as a direct NAD+ precursor. Human clinical trials demonstrate that NR supplementation safely and meaningfully supports NAD+ levels in blood and tissue. [1] Critically, NR does not stimulate energy directly — it supports the cell’s capacity to produce energy through normal metabolic pathways. This distinction matters for long-term daily use without dependency or tolerance.†
Silbinol® Pterostilbene — cellular defense
Pterostilbene from Pterocarpus marsupium supports antioxidant defense and metabolic signaling including sirtuin pathways. [4] Its methylated structure confers significantly higher oral bioavailability than resveratrol — making it more effectively utilized at the cellular level.†
Direct NAD+ precursor. Dose aligns with human clinical trials showing meaningful NAD+ support and good tolerability for sustained daily use.†
Trammell SA et al. Nat Commun 2016 [1]Supports antioxidant defense and sirtuin-related metabolic signaling. Higher bioavailability than resveratrol due to methylated structure.†
McCormack D et al. OMCL 2012 [4]Osmolyte and methyl donor supporting cellular hydration and methylation pathways. Works synergistically with the active B-vitamin system in MYO Daily.†
Hoffman JR et al. JISSN 2009 [2]P-5-P, L-5-MTHF, and methylcobalamin — bioactive forms that bypass conversion, critical for adults with declining digestive efficiency.†
Stach K et al. PMC 2024 (PMC11173557) [8]The gut-muscle connection
Short-chain fatty acids (SCFAs), produced when gut bacteria ferment prebiotic fiber, support gut barrier integrity, modulate systemic inflammation, and influence nutrient availability to muscle tissue. Research shows microbiome composition directly affects protein utilization and metabolic outcomes. [7,8] A formula built for muscle that ignores the gut is a formula working against itself.
Why this fiber system — and not inulin or FOS
Fibalance™ PHGG (partially hydrolyzed guar gum) is one of the most clinically studied and highly tolerated prebiotic fibers available. Unlike inulin and FOS — which ferment rapidly and commonly cause bloating — PHGG ferments more slowly, producing SCFA benefits without the GI friction that drives consumer dropout. For a protein formula consumed daily, tolerability is essential. [9]
Isolates, enzymes, and the absorption advantage
Plant protein concentrates retain anti-nutritional compounds including phytates and lectins, which reduce mineral absorption and can irritate gut tissue. Isolates remove the majority of these fractions, improving amino acid bioavailability and digestive tolerance. The digestive enzyme blend further supports complete digestion of plant proteins, fibers, and lipids — maximizing what actually reaches muscle.†
Clinically supported prebiotic fiber. Highly tolerated — supports gut regularity and microbiome health without the bloating common with inulin or FOS.†
Martinsen TC et al. Clin Nutr 2020 [9]Organic soluble fiber supporting SCFA production and gut barrier integrity. Well-tolerated alternative to high-fermentation fiber sources.†
Slavin J. Nutrients 2013 [7]Medium chain triglycerides rapidly metabolized for energy. Supports satiety and fat-soluble nutrient absorption alongside the vitamin system.†
Clegg ME. BJN 2010 [8]Broad-spectrum enzyme complex. Addresses age-related decline in digestive enzyme production — maximizing absorption of protein, fiber, and lipids.†
Martinez I et al. AJCN 2010 [8b]Declining nutritional density in the modern food supply
Decades of research document declining mineral content in conventionally grown produce — a result of soil depletion, monoculture farming, and accelerated growing cycles. Magnesium, zinc, and B-vitamins show the most consistent reductions compared to measurements from 50 years ago. Combined with food processing and the pace of modern life, the baseline nutritional environment for adults in midlife is genuinely more challenging than it was for previous generations.
The leucine gap on plant-forward diets
Hitting the post-40 leucine threshold of 2.5–3g per meal consistently from food alone is difficult — particularly on plant-forward diets. Most plant protein sources are leucine-limited relative to animal sources. MYOCODE Protein adds vegan L-leucine directly to close this gap rather than relying on food intake alone. [6]
What MYOCODE provides across both products
Together, MYOCODE Protein and MYO Daily fill specific micronutrient gaps with clinical intention: magnesium bisglycinate for muscle function and ATP production; vitamins D3 and K2 working synergistically for musculoskeletal health; natural vitamin C for collagen and connective tissue; electrolytes for muscle contraction and cellular hydration; active B-vitamins for methylation and energy metabolism; and chromium for healthy metabolic function. Nothing is included for label appeal. Everything has a reason.†
Required for muscle contraction, ATP production, and protein synthesis. Bisglycinate form chosen for high bioavailability and GI tolerance vs. inferior magnesium salts.†
Schuette SA et al. JPEN 1994; PubMed 7932463 [13]Work synergistically for calcium utilization, bone mineralization, and muscle fiber function. Vegan-sourced D3 — rare in plant-based formulas.†
Halder M et al. PMC 2017; PMC5613455 [14]Natural-source vitamin C at 110% DV. Supports collagen synthesis and connective tissue integrity. Whole-food source aligned with clean-label positioning.†
DePhillipo NN et al. Orthop J Sports Med 2018; PMC6204628 [15]Supports healthy metabolic function and nutrient partitioning — completing the metabolic environment in which muscle building occurs.†
Cefalu WT et al. Diabetes Care 2006; PubMed 16873787 [16]Scientific References
All clinical claims on this page are supported by peer-reviewed research. References are listed below by pillar. Citations [8] and [13]–[16] reference peer-reviewed published research confirming the bioavailability and clinical rationale for each ingredient form selected.
The science is here.
The system is ready.
MYOCODE was built on this research — at clinical doses, with clinical-grade ingredients, refined over nine months until it was right.
People who decided the story
didn’t have to end that way.
Real results from real people using the MYOCODE system.
† These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease. myHMB® is a registered trademark of TSI Group Co., Ltd. SILBINOL® is a registered trademark of Sabinsa Corporation, USA. Fibalance™ is a trademark of ECA Healthcare / Zymebase. FiberSMART® is a registered trademark of Anderson Advanced Ingredients. goMCT® is a registered trademark of Compound Solutions, Inc.